Is there a role of MRI in Head Neck Cancers ? Which patients apart from Nasopharynx do you think MRI is helpful ?
Can pretreatment MR-spectroscopy and dynamic contrast enhanced MRI help in knowing Tumor Metabolism and Perfusion in Head and Neck Squamous Cell Carcinoma ?
Wanted to know how many of you actually think this will work and are looking at using these imaging tools.
Hi,
There is a role of MRI in head and neck cancers apart from Npx.
The main advantage of MRI over CT scan is the superior soft tissue delineation. The obvious downside is the expense, scanning time, inability to do RT planning.
I believe MRI is useful in the oropharyngeal malignancies, especially so in BOT lesion. CT has poor visualisation in this area and MRI images can help to see the infiltration into the tongue muscles. In patients treated with IMRT, where the margins are conservative, I always prefer to have MRI done pre RT planning. MRI in this particular setting is much better that PET/CT also. In tonsillar ca, it helps to contour primary, especially the lateral extent.
I think the role in laryngeal malignancies is limited as CT scan or PET/CT can give good images.
Use of spectroscopy, perfusion scan is more for differentiating between recurrence and post RT changes. I dont think it will add any extra clinically relevant information. DW and DCE data can be integrated to know the functional aspect of the tumour but the evidence is still building on that.
Prasad
I agree with this.
MRI is exceptional for delineating soft tissues specifically for:
- organ boundaries
- infiltration of muscles
- infiltration of fat
- infiltration along nerves
- infiltration of bone marrow
- mitigation of teeth fillings
It is particularly useful if you can get MRI done in the treatment position (?ask MRI unit to institute RT-friendly positioning protocol). You need to do some research on previous scans to identify the best sequence for tumour delineation.
PET/CT is most useful for identifying an involved organ, not for delineating margins. The acquisition time is long and so margins are fuzzy2 (fuzzy images smeared by movement artifact).
A case of infiltrating ductal ca left breast in a 73 year old patient ,operated twice wide excision and which was followed by MRM, HPE - margin negative , grade III, ER + , PR-, Her 2 neu +, LVI +, PNI+,one axillary node + out o 16 , KPS 80, Diabetic , Hypertensive, What should be the adjuvant treatment?
Thanks for your inputs. I do agree MRI is good, infact people are looking at diffusion weighted MRI's too.