Breast Conservation in Locally Advanced Breast Cancer

Summary:

How strong is the evidence for doing Neo-adjuvant chemo followed by BCS ?

Breast Conservation in Locally Advanced Breast Cancer

Nikhilesh Patil 10 Sep 2010 23:37

Guys,
For LABC, I was trained with the concept of NACT(3-4 cycles)—-BCS if good response and then complete chemo and RT.
Mastectomy was reserved for patients who had poor response to NACT or if there are other standard contraindications for BCS (mulitfocality, tumor breast ratio, etc.,). However breast surgeons in Canada do not agree to this treatment plan, they do upfront Mastectomy which sounds a bit different than what I learned.

Can anyone tell me do we have strong evidence to support breast conserving therapy in locally advanced breast cancer ? or is this an grey area still?

Nikhilesh

Re: Breast Conservation in Locally Advanced Breast Cancer

Rohit Malde 11 Sep 2010 00:51

Present this in your Journal club which have surgeons attending as well. An excellent review article.

Alm El-Din, M, Taghian, A. Breast conserving therapy for patients with locally advanced breast cancer. Semin Radiat Oncol 2009; 19:229