Breast Conservation in Locally Advanced Breast Cancer http://isocentre.wikidot.com/forum/t-264359/breast-conservation-in-locally-advanced-breast-cancer Posts in the discussion thread "Breast Conservation in Locally Advanced Breast Cancer" - How strong is the evidence for doing Neo-adjuvant chemo followed by BCS ? Fri, 04 Sep 2026 14:54:08 +0000 http://isocentre.wikidot.com/forum/t-264359#post-869782 Re: Breast Conservation in Locally Advanced Breast Cancer http://isocentre.wikidot.com/forum/t-264359/breast-conservation-in-locally-advanced-breast-cancer#post-869782 Sat, 11 Sep 2010 00:51:25 +0000 Rohit Malde 418807 Present this in your Journal club which have surgeons attending as well. An excellent review article.

Alm El-Din, M, Taghian, A. Breast conserving therapy for patients with locally advanced breast cancer. Semin Radiat Oncol 2009; 19:229

]]> http://isocentre.wikidot.com/forum/t-264359#post-869740 Breast Conservation in Locally Advanced Breast Cancer http://isocentre.wikidot.com/forum/t-264359/breast-conservation-in-locally-advanced-breast-cancer#post-869740 Fri, 10 Sep 2010 23:37:09 +0000 Nikhilesh Patil 416151 Guys,
For LABC, I was trained with the concept of NACT(3-4 cycles)—-BCS if good response and then complete chemo and RT.
Mastectomy was reserved for patients who had poor response to NACT or if there are other standard contraindications for BCS (mulitfocality, tumor breast ratio, etc.,). However breast surgeons in Canada do not agree to this treatment plan, they do upfront Mastectomy which sounds a bit different than what I learned.

Can anyone tell me do we have strong evidence to support breast conserving therapy in locally advanced breast cancer ? or is this an grey area still?

Nikhilesh

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