Brachytherapy for Intermediate Risk Prostate Cancer http://isocentre.wikidot.com/forum/t-256449/brachytherapy-for-intermediate-risk-prostate-cancer Posts in the discussion thread "Brachytherapy for Intermediate Risk Prostate Cancer" Fri, 15 May 2026 17:06:59 +0000 http://isocentre.wikidot.com/forum/t-256449#post-869760 Re: Brachytherapy for Intermediate Risk Prostate Cancer http://isocentre.wikidot.com/forum/t-256449/brachytherapy-for-intermediate-risk-prostate-cancer#post-869760 Sat, 11 Sep 2010 00:19:38 +0000 Rohit Malde 418807 Nikhilesh,

The debate i believe in this risk group is whether EBRT + Brachy is superior to EBRT alone or Brachy alone.

1. Hoskin et al have already shown in Ph 3 trial, that EBRT + Brachy boost is superior to RT alone.
http://cat.inist.fr/?aModele=afficheN&cpsidt=19038384

2. The RTOG 0232 are proposing to prove that EBRT + Brachy alone is gnna be superior to Brachy alone.
If you look at their statistcal proposotion they beleive EBRT plus interstitial brachytherapy will improve a FFP rate at 5 years
compared to interstitial brachytherapy alone by 10% with an α value of 0.025 (one-sided), statistical power of 90%.

This trial is gonna be controversial as Brachy alone is being used here as the std arm
and the experimental arm is EBRT + Brachy which allows IMRT as well as 3DCRT.

]]> http://isocentre.wikidot.com/forum/t-256449#post-869745 Re: Brachytherapy for Intermediate Risk Prostate Cancer http://isocentre.wikidot.com/forum/t-256449/brachytherapy-for-intermediate-risk-prostate-cancer#post-869745 Fri, 10 Sep 2010 23:48:45 +0000 Nikhilesh Patil 416151 Iam still waiting for people to tell me if you guys offer brachytherapy for intermediate risk prostate cancer patients.

]]> http://isocentre.wikidot.com/forum/t-256449#post-840584 Brachytherapy for Intermediate Risk Prostate Cancer http://isocentre.wikidot.com/forum/t-256449/brachytherapy-for-intermediate-risk-prostate-cancer#post-840584 Sun, 01 Aug 2010 05:36:00 +0000 Nikhilesh Patil 416151 Dear all,
I would like to know your thoughts about Brachytherapy alone for good Intermediate Risk Prostate Cancer patients. Anyone of you using brachy alone for these patients. Iam aware of RTOG 0232 study http://rtog.org/members/protocols/0232/0232.pdf which is looking at this question.
Your comments are welcome
Nikhilesh

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